Simultaneous determination of quinine and four metabolites in plasma and urine by high-performance liquid chromatography
- 21 March 2001
- journal article
- Published by Elsevier in Journal of Chromatography B: Biomedical Sciences and Applications
- Vol. 754 (1), 57-64
- https://doi.org/10.1016/s0378-4347(00)00577-6
Abstract
No abstract availableKeywords
This publication has 9 references indexed in Scilit:
- The roles of cytochrome P450 3A4 and lA2 in the 3-hydroxylation of quinine in vivoClinical Pharmacology & Therapeutics, 1999
- Identification of quinine metabolites in urine after oral dosing in humansJournal of Chromatography B: Biomedical Sciences and Applications, 1998
- High-performance liquid chromatographic method for the determination of the major quinine metabolite, 3-hydroxyquinine, in plasma and urineJournal of Chromatography B: Biomedical Sciences and Applications, 1998
- Evidence for involvement of human CYP3A in the 3‐hydroxylation of quinineBritish Journal of Clinical Pharmacology, 1997
- Metabolism of Quinine in Man: Identification of a Major Metabolite, and Effects of Smoking and Rifampicin PretreatmentJournal of Pharmacy and Pharmacology, 1995
- Characterization of the principal metabolite of quinine in human urine by 1 H-n.m.r. spectroscopyXenobiotica, 1991
- Synthesis of 10, 11-Dihydroxydihydroquinidine N-oxide, a New Metabolite of Quinidine. Preparation and 1H-nmr Spectroscopy of the Metabolites of Quinine and Quinidine and Conformational Analysis via 2D COSY NMR SpectroscopyJournal of Natural Products, 1990
- High-performance liquid chromatographic separation and isolation of quinidine and quinine metabolites in rat urineJournal of Chromatography B: Biomedical Sciences and Applications, 1980
- Synthesis and stereochemistry of a metabolite resulting from the biotransformation of quinidine in manTetrahedron Letters, 1976