Role of leader peptide synthesis in tryptophanase operon expression in Escherichia coli K-12
Open Access
- 30 June 1986
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 167 (1), 383-386
- https://doi.org/10.1128/jb.167.1.383-386.1986
Abstract
We used site-directed mutagenesis to replace the Escherichia coli tryptophanase (tna) operon leader peptide start codon with AUC. This change greatly decreased the uninduced rate of tna operon expression, and it also lowered the response to inducer. We conclude that leader peptide synthesis plays an essential role in tna operon expression.This publication has 30 references indexed in Scilit:
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