Closing capacity in awake and anesthetized-paralyzed man
- 1 February 1978
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 44 (2), 238-244
- https://doi.org/10.1152/jappl.1978.44.2.238
Abstract
Functional residual capacity (FRC), closing capacity (CC) and (FRC - CC) were determined in 61 supine patients using the 133Xe bolus test. In 28 of the 61 patients measurements were made both while the patients were awake and during anesthesia-paralysis. Both FRC and CC significantly decreased after induction of anesthesia-paralysis. The magnitude of the reduction in CC, but not of FRC, was dependent on the relationship between FRC and CC in the awake state. Patients whose FRC was larger than their CC while awake (group I) showed less decrease in CC than FRC, i.e., (FRC - CC) decreased. Those patients whose CC was larger than their FRC while awake (group II) showed a greater decrease in CC than in FRC, i.e., (FRC - CC) became less negative. The reduction in CC after induction of anesthesia-paralysis may result from an increased elastic recoil of the lung. The larger reduction in CC in group II patients may have been due to a larger increase in elastic recoil, possibly due to the development of atelectasis.This publication has 10 references indexed in Scilit:
- Regional intrapulmonary gas distribution in awake and anesthetized-paralyzed manJournal of Applied Physiology, 1977
- Effect of inspired volume on closing volumeJournal of Applied Physiology, 1976
- Influence of bronchomotor tone on regional ventilation distribution at residual volumeJournal of Applied Physiology, 1976
- INFLUENCE OF BRONCHOMOTOR TONE ON VENTILATION DISTRIBUTION AND AIRWAY-CLOSURE IN ASYMPTOMATIC ASTHMAPublished by Elsevier ,1976
- Solubility of Xenon-133 at 37°C in Water, Saline, Olive Oil, Liquid Paraffin, Solutions of Albumin, and BloodPhysics in Medicine & Biology, 1967
- Regional ventilation of the lung, studied with boluses of 133xenonRespiration Physiology, 1967
- Influence of lung parenchyma on pressure-diameter behavior of dog bronchi.Journal of Applied Physiology, 1966
- Regional distribution of inspired gas in the lung.Journal of Applied Physiology, 1966
- Effect of lung inflation on static pressure-volume characteristics of pulmonary vesselsJournal of Applied Physiology, 1961
- Ventilation Standards for Use in Artificial RespirationJournal of Applied Physiology, 1955