Replantation of Uterus and Ovaries in Dogs, With Successful Pregnancy

Abstract

TRANSPLANTATION. RANSPLANTATION of the ovary has been reported by a number of investigators.^1-4 Ovarian autoimplants in the peritoneal cavity may acquire sufficient parasitic blood supply to permit ovulation and successful pregnancy. Ovarian homotransplants provide temporary evidence of hormonal production,^5,6 but they are eventually rejected.⁷ In contrast to those on ovarian transplantation, studies involving uterine transplantation have been few. In fact, we had found no such work in the available literature at the time we began our investigations. However, in April 1964, Zhordania and Gotsiridze⁸ reported successful replantation of the uterus and its appendages in rabbits, dogs, and especially in sheep. They used omentopexy for revascularization and achieved successful pregnancy in some instances. Nevertheless, our studies apparently represent the first in which vascular anastomoses were used for successful uterine replantation. The efficacy of the several anastomoses were supported by aortography, hysterography, studies of vaginal epithelium, evidence of