The Second Extracellular Loop of the Prostaglandin EP3 Receptor Is an Essential Determinant of Ligand Selectivity
Open Access
- 1 May 1997
- journal article
- Published by Elsevier
- Vol. 272 (21), 13475-13478
- https://doi.org/10.1074/jbc.272.21.13475
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Substitution of Charged Amino Acid Residues in Transmembrane Regions 6 and 7 Affect Ligand Binding and Signal Transduction of the Prostaglandin EP3ReceptorPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,1997
- Mutagenic Analysis of Platelet Thromboxane Receptor CysteinesPublished by Elsevier ,1996
- Molecular architecture of G protein-coupled receptorsDrug Development Research, 1996
- Selective Coupling of Prostaglandin E Receptor EP3D to Gi and Gs through Interaction of α-Carboxylic Acid of Agonist and Arginine Residue of Seventh Transmembrane DomainPublished by Elsevier ,1995
- Expression and site-directed mutagenesis of mouse prostaglandin E2 receptor EP3 subtype in insect cellsBiochemical Journal, 1995
- Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.Published by Elsevier ,1994
- Structure and function of receptors coupled to G proteinsCurrent Opinion in Cell Biology, 1994
- The extracellular domain of the neurokinin-1 receptor is required for high-affinity binding of peptidesBiochemistry, 1992
- Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function.Proceedings of the National Academy of Sciences, 1991
- Site-directed Mutagenesis of β-Adrenergic ReceptorsPublished by Elsevier ,1989