Effect of Reserpine (Serpasil(R)) on Oxygen Consumption of Euthyroid, Hypothyroid, and Hyperthyroid Guinea Pigs

Abstract

O2 consumption was reduced to hypothyroid levels in reserpine-treated euthyroid and hyperthyroid guinea pigs, but no significant changes were noted in the reserpine-treated hypothyroid animals. The evidence presented and discussed suggests that reserpine antagonized the effect of thyroid hormone on O2 consumption.