Blocking Action of Tetraethylammonium on Axon Reflexes in the Human Skin
- 7 January 1949
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 109 (2819), 16
- https://doi.org/10.1126/science.109.2819.16
Abstract
In 15 expts. on 7 subjects, infiltration of skin with tetraethylammonium followed by injn. of acetylcholine inhibited pilomotion whereas controls receiving only acetylcholine exhibited typical pilomotion. In a series of 12 expts. on 8 subjects axon reflex sweating was either completely inhibited or markedly suppressed when acetylcholine was injd. into the spot previously injd. with tetraethylammonium. Control areas not previously treated with tetraethylammonium produced typical axon sweating. The possible site of block and specificity of the blocking effect is discussed.Keywords
This publication has 4 references indexed in Scilit:
- THE EFFECTS OF BLOCKADE OF THE AUTONOMIC GANGLIA IN MAN WITH TETRAETHYLAMMONIUMThe American Journal of the Medical Sciences, 1947
- THE ACTION OF TETRAETHYLAMMONIUM ION ON THE MAMMALIAN CIRCULATION1946
- THE BLOCKING EFFECT OF TETRAETHYLAMMONIUM ION ON THE SUPERIOR CERVICAL GANGLION OF THE CAT1946
- Axon Reflex Responses to Acetyl Choline in the Skin11From the Section of Dermatology of the Department of Medicine, and the Department of Pharmacology, University of Chicago. Read before the Second Annual Meeting of the Society for Investigative Dermatology, Inc., St. Louis, Missouri, May 16,1939. This work was aided in part by grants from the Commonwealth Fund, and the Dr. Wallace C. and Clara A. Abott Memorial Fund of the University of Chicago.Journal of Investigative Dermatology, 1940