Large-Scale Synthesis of Oligodeoxyribonucleotide Phosphorothioate Using Controlled-Pore Glass as Support
- 1 August 1995
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 14 (6), 1219-1226
- https://doi.org/10.1080/15257779508010685
Abstract
An efficient synthesis of oligonucleotide phosphorothioate on a very large-scale using controlled-pore glass as support is described.Keywords
This publication has 24 references indexed in Scilit:
- Efficient synthesis of antisense oligodeoxyribonucleotide phosphorothioatesBioorganic & Medicinal Chemistry Letters, 1994
- Rapid Sequencing of Oligonucleotides by High-Resolution Mass SpectrometryJournal of the American Chemical Society, 1994
- Stepwise Regeneration and Recovery of Deoxyribonucleoside Phosphoramidite Monomers During Solid-Phase Oligonucleotide SynthesisThe Journal of Organic Chemistry, 1994
- The analysis of mock DNA sequencing reactions using matrix‐assisted laser desorption/ionization mass spectrometryRapid Communications in Mass Spectrometry, 1993
- Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?Science, 1993
- Oligonucleotide analysis by gel capillary electrophoresisMethods, 1992
- The automated synthesis of sulfur-containing oligodeoxyribonucleotides using 3H-1,2-benzodithiol-3-one 1,1-dioxide as a sulfur-transfer reagentThe Journal of Organic Chemistry, 1990
- 3H-1,2-Benzodithiole-3-one 1,1-dioxide as an improved sulfurizing reagent in the solid-phase synthesis of oligodeoxyribonucleoside phosphorothioatesJournal of the American Chemical Society, 1990
- Separation of oligonucleotides by high-performance ion-exchange chromatography on a non-porous ion exchangerJournal of Chromatography A, 1988
- The purification of oligodeoxyribonucleotides with a high guanosine content by anion exchange HPLCBiochimie, 1985