A Second Outbreak of Boston Exanthem Disease in Pittsburgh during 1954

Abstract

A PREVIOUS report¹ described an unusual epidemic exanthem that occurred during the late summer of 1951 in Boston. Evidence then available indicated that the illness represented a clinical entity different from the more commonly known exanthems. In addition, the isolation of a new group of transferable agents from feces of several of the patients, as well as their neutralizing-antibody responses, suggested a possible etiologic relation of these agents to the disease.These initial observations have now been corroborated and extended by studies of a second outbreak of a similar clinical entity observed in Pittsburgh during June to September, 1954. Filterable . . .