Isolation of adenine-desoxyriboside from thymusnucleic acid

Abstract

A modified method, considerably shortening the isolation of adenine-desoxyriboside from thymusnucleic acid is descr. The hydrolysed thymusnucleic acid, Klein (1938) Hoppe-Seyl. Z., 255, 82, is extracted with alc. After removal of the alc., the residue is dissolved in aq. acetone from which adenine-desoxyriboside crystallises on standing over-night in the refrigerator. It sinters at 162[degree] and melts at 187[degree]-8[degree]. This is considerably higher than the M.P. recorded by Klein (1934). Hoppe-Seyl. Z. 224, 244.