RNA polymerase associated with human rotaviruses in diarrhea stools

Abstract

RNA polymerase activity was detected in 6 stools which were partially purified by high-speed centrifugation from infants with rotavirus gastroenteritis, but was not detected in 5 stools which were negative for rotavirus by counter-immunoelectrophoresis and radioimmunoassay. The polymerase activity was associated with the 1.38 g/ml rotavirus band after purification in a CsCl gradient.