The tripartite motif family identifies cell compartments
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- 1 May 2001
- journal article
- research article
- Published by Springer Nature in The EMBO Journal
- Vol. 20 (9), 2140-2151
- https://doi.org/10.1093/emboj/20.9.2140
Abstract
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a tripartite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo‐multimerization they identify specific cell compartments.Keywords
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