THE INHERITANCE AND DEVELOPMENT OF CUP AND DISC DIAMETERS
- 27 May 2009
- journal article
- research article
- Published by Wiley in Acta Ophthalmologica
- Vol. 58 (5), 733-739
- https://doi.org/10.1111/j.1755-3768.1980.tb06686.x
Abstract
The familial resemblances in disc diameter (d) and cup diameter residual (e) were studied in 845 individuals forming 297 families and 1040 pairs of spouses and 1st-degree relatives. The cup diameter residual was computed as the difference between the observed cup diameter and the cup diameter expected from the disc diameter and the age, according to a multiple regression equation. The results for d and e were similar. Spouses did not resemble each other at all. The resemblance between 1st-degree relatives was quite substantial. There were no major influences of sex-linkage, dominance or common environment, and no obvious maternal effects. The familial resemblance was essentially additively genetic in origin. The heritability was estimated at 2/3. The remaining variance was attributed to errors of development. Other surface dimensions of the optic nerve head are related.Keywords
This publication has 7 references indexed in Scilit:
- THE ALTERATION AND ASYMMETRY OF CUP AND DISC DIAMETERSActa Ophthalmologica, 1980
- Familial Resemblance in Casual Blood Pressure—a Maternal Effect?Clinical Science, 1979
- OPTIC DISC CUPPING AND PREMATURITY Large Cups as a Possible Low Birth Weight SequelActa Ophthalmologica, 1978
- SOME ESSENTIAL OPTICAL FEATURES OF THE ZEISS FUNDUS CAMERAActa Ophthalmologica, 1977
- THE VARIATION AND COVARIATION OF CUP AND DISC DIAMETERSActa Ophthalmologica, 1976
- RESEMBLANCE BETWEEN TONOMETER READINGS ON RELATIVES AND SPOUSESActa Ophthalmologica, 1976
- Size of the Physiologic Cup of the Optic Nerve HeadArchives of Ophthalmology (1950), 1975