Sterility Induced in Growing Rats on a Tryptophane-deficient Diet

Abstract

3 groups of mice were acclimated to temps. of 13[degree], 22[degree] and 32[degree] C, and then injd. intracerebrally with 0.05 ml. of 3% infected brain-cord suspension. Mice acclimated to 13[degree] and held at that temp. after injn. showed no symptoms of paralysis in < 11 days; mortality was 50% in 13 days. Mice adapted to 22[degree] and held there after injn. showed 50% mortality after 7 days, and mice held at 32[degree] began to die as early as the 5th day. Mice acclimated to 13[degree] and kept at 22[degree] and 32[degree] after injn. were more susceptible than those held at 13[degree]. Mice adapted to 22[degree] and 32[degree] had more resistance when kept at 13[degree] than when held at 22[degree] and 32[degree].