Dementia Associated with Human Immunodeficiency Virus with a Negative ELISA

Abstract

To the Editor: Dementia as part of the acquired immunodeficiency syndrome (AIDS) is becoming recognized as a serious clinical as well as diagnostic problem.¹ In fact, patients are now being described who may present with serious neurologic abnormalities before the development of AIDS as defined by the Centers for Disease Control.² We wish to report a case of progressive dementia that was not recognized as a disease related to human immunodeficiency virus (HIV, or HTLV-III/LAV) because of a negative serologic study of the patient's blood with the enzyme-linked immunosorbent assay (ELISA).A 57-year-old unmarried man noted progressive memory loss, sleep . . .