HLA and Mycobacterial Infection: Increased Frequency of B8 in Japanese Leprosy*
- 1 January 1978
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 11 (1), 61-64
- https://doi.org/10.1111/j.1399-0039.1978.tb01225.x
Abstract
Sixty leprosy patients (28 of lepromatous and 32 of tuberculoid form) and 70 active tuberculosis patients were compared with a control of 184 for 34 HLA specificities. There was an increased frequency (10.0%) for HLA-B8 (corrected P = 0.062, relative risk = 20.3) in the leprosy patients as compared with the control group, despite the fact that the frequency of HLA-B8 was extremely low in Japanese. All leprosy patients with B8 had leprous member(s) in their family.This publication has 7 references indexed in Scilit:
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- Distribution of some of the HL‐A System Lymphocyte Antigens in MexicansVox Sanguinis, 1973