Pituitary Responsiveness to LH-RH in Post-partum Ewes Treated With Oestradiol-17ß and Failing to Show a Plasma LH Surge
Open Access
- 1 January 1980
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Biological Sciences
- Vol. 33 (4), 465-470
- https://doi.org/10.1071/bi9800465
Abstract
Estradiol-17.beta. (40 .mu.g i.v.) failed to elicit a surge in plasma LH [luteinizing hormone, lutropin] levels by 13 h after administration in 64% (16 of 25) Merino ewes, .apprx. 30 days post partum in the anestrous season. LH-RH [luteinizing hormone-releasing hormone, luliberin] responsiveness and LH-RH priming effect was significantly greater in these ewes than in similar post partum (no. = 9) and non-parturient ewes (no. = 3) not treated with estradiol. Apparently, the failure of the estrogen-positive feedback effect on LH release in post partum ewes is not due to a failure of estradiol action on the pituitary increasing pituitary responsiveness to LH-RH and LH-RH priming effect, but could be due to inadequate release of LH-RH from the hypothalamus.Keywords
This publication has 10 references indexed in Scilit:
- Failure of Estrogen-Induced Discharge of Luteinizing Hormone in Lactating WomenJournal of Clinical Endocrinology & Metabolism, 1979
- Ovarian function in suckling and non-suckling beef cows post partumReproduction, 1978
- Differential Responsiveness to LRF after Estrogen Therapy in Women with Hypothalamic AmenorrheaJournal of Clinical Endocrinology & Metabolism, 1978
- A priming effect of LH-RH on the pituitary in ramsReproduction, 1977
- Luteinizing Hormone Releasing Hormone (LHRH) in Pituitary Stalk Blood of Rhesus Monkeys: Relationship to Level of LH Release1Endocrinology, 1977
- Pituitary responsiveness to synthetic LH-RH and pituitary LH content at various reproductive stages in the sheepReproduction, 1977
- THE CONTROL OF GONADOTROPHIN RELEASE IN WOMEN WITH HYPERPROLACTINAEMIC AMENORRHOEA: EFFECT OF OESTROGEN AND PROGESTERONE ON THE LH AND FSH RESPONSE TO LHRHClinical Endocrinology, 1976
- The influence of prostaglandin F-2 on pregnenolone metabolism by the autotransplated ovary of the eweReproduction, 1976
- Content of LH, FSH, and Growth Hormone in the Pituitaries of Pregnant and Anestrous SheepEndocrinology, 1976
- THE PITUITARY RESPONSE TO EXOGENOUS LUTEINIZING HORMONE RELEASING FACTOR IN STEROID-TREATED GONADECTOMIZED RATSJournal of Endocrinology, 1976