Pain Relief in the Post-Operative Period: A Comparative Trial of Morphine and a New Analgesic Buprenorphine

Abstract

In a comparative trial, buprenorphine 0.3 mg or morphine 10 mg was administered intramuscularly to patients post operatively. The new drug buprenorphine produced more pain relief than morphine and appeared to have a longer duration of action. The side-effects produced by the two drugs were similar, as were the effects on respiratory and cardiovascular measurements.