Linkage studies in X-linked Alport's syndrome
- 1 December 1988
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 81 (1), 85-87
- https://doi.org/10.1007/bf00283736
Abstract
Four kindreds segregating for Alport's syndrome (ASLN) compatible with a X-linked inheritance were studied for linkage with polymorphic markers of the human X chromosome. No recombinant was observed between the ASLN locus and the DXS101 and DXS94 loci, the maximum lod scores were z=3.93 and 3.50 respectively. Linkage data between the ASLN locus and the other genetic markers used in the present study are in keeping with the assignment of the mutation to the proximal Xq arm.Keywords
This publication has 17 references indexed in Scilit:
- Genetic mapping of nine DNA markers in the q11 → q22 region of the human X chromosomeGenomics, 1987
- An interstitial duplication of the X chromosome in a male allows physical fine mapping of probes from the Xq13-q22 regionHuman Genetics, 1987
- Investigation of Genetic Linkage in Human FamiliesPublished by Springer Nature ,1987
- Genetics of Alport's syndromePediatric Nephrology, 1987
- The 1987 Catalog of Mapped Genes and Report of the Nomenclature Committee (Part 1 of 4)Cytogenetic and Genome Research, 1987
- Genetic heterogeneity of Alport syndromeKidney International, 1985
- Report of the committee on the genetic constitution of the X and Y chromosomesCytogenetic and Genome Research, 1985
- Report of the committee on methods of linkage analysis and reportingCytogenetic and Genome Research, 1985
- Strategies for multilocus linkage analysis in humans.Proceedings of the National Academy of Sciences, 1984
- Diminished vascular response to noradrenaline in experimental chronic uremiaKidney International, 1982