Factor VIII Activity and Factor VIII-Related Antigen in Infants with Viral Bronchiolitis
- 8 November 1984
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 311 (19), 1257-1258
- https://doi.org/10.1056/nejm198411083111916
Abstract
To the Editor: Levels of factor VIII–related antigen (VIIIR:Ag) and factor VIII activity (VIII:C) increase in stressful conditions, such as physical exercise,1 and in respiratory failure due to the respiratory-distress syndrome in newborns2 as well as in other clinical disorders.3 , 4 While studying adults with acute respiratory diseases, Carvalho et al. observed that VIIIR:Ag levels were five times normal, and suggested that this finding indicated pulmonary endothelial damage.5 We studied 26 infants (16 to 108 days old) with viral bronchiolitis. The course of the illness was critical during the 96 hours after onset; recovery occurred in 8 to 10 days in . . .Keywords
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