Stealth PLA-PEG Nanoparticles as Protein Carriers for Nasal Administration
- 1 January 1998
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 15 (2), 270-275
- https://doi.org/10.1023/a:1011922819926
Abstract
Purpose. The aim of the study was to encapsulate a model protein antigen, tetanus toxoid (TT), within hydrophobic (PLA) and surface hydrophilic (PLA-PEG) nanoparticles and to evaluate the potential...Keywords
This publication has 12 references indexed in Scilit:
- The Oral Absorption of Micro- and Nanoparticulates: Neither Exceptional Nor UnusualPharmaceutical Research, 1997
- Nasal Delivery of VaccinesJournal of Drug Targeting, 1996
- Stealth Me. PEG‐PLA Nanoparticles Avoid Uptake by the Mononuclear Phagocytes SystemJournal of Pharmaceutical Sciences, 1995
- Biodegradable Long-Circulating Polymeric NanospheresScience, 1994
- Surface Modification of Poly(lactide-co-glycolide) Nanospheres by Biodegradable Poly(lactide)-Poly(ethylene glycol) CopolymersPharmaceutical Research, 1994
- Immune Response to Nasal Delivery of Antigenically Intact Tetanus Toxoid Associated with Poly(l-lactic acid) Microspheres in Rats, Rabbits and Guinea-pigsJournal of Pharmacy and Pharmacology, 1993
- Determinants of Release Rate of Tetanus Vaccine from Polyester MicrospheresPharmaceutical Research, 1993
- Intranasal immunization with bacterial polysaccharide containing liposomes enhances antigen-specific pulmonary secretory antibody responseVaccine, 1992
- The role of nasopharyngeal lymphoid tissueImmunology Today, 1992
- [The transnasal route of drug administration. Aspects of nasal anatomy and physiology].1989