Necrotizing Enterocolitis in 20 822 Infants: Analysis of Medical and Surgical Treatments
- 14 January 2010
- journal article
- Published by SAGE Publications in Clinical Pediatrics
- Vol. 49 (2), 166-171
- https://doi.org/10.1177/0009922809349161
Abstract
Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency of the neonate. Previous information about this disease has largely been gathered from limited series. We analyzed 13 years of the National Inpatient Sample (NIS) and 3 years of the Kids’ Inpatient Database (KID; 1997, 2000, 2003) to generate the most comprehensive profile of outcomes to date of medically versus surgically treated NEC. We identified 20 822 infants with NEC, of whom 15 419 (74.1%) and 5403 (25.9%) were undergoing medical and surgical management, respectively. Overall, surgical patients had greater length of stay, total hospital charges, and mortality. Among infants dying during admission, there was no significant difference in length of stay or charges between the medical and surgical groups. These findings highlight the need for developing a clinically relevant risk stratification tool to identify NEC patients at high risk for death.Keywords
This publication has 16 references indexed in Scilit:
- Necrotising enterocolitis hospitalisations among neonates in the United StatesPaediatric and Perinatal Epidemiology, 2006
- Laparotomy versus Peritoneal Drainage for Necrotizing Enterocolitis and PerforationNew England Journal of Medicine, 2006
- Laparotomy Versus Peritoneal Drainage for Necrotizing Enterocolitis or Isolated Intestinal Perforation in Extremely Low Birth Weight Infants: Outcomes Through 18 Months Adjusted AgePediatrics, 2006
- New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposureJournal of Perinatology, 2005
- Very Low Birth Weight Outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 Through December 1996Pediatrics, 2001
- Salvage laparotomy for failure of peritoneal drainage in necrotizing enterocolitis in infants with extremely low birth weightJournal of Pediatric Surgery, 2000
- Peritoneal drainage as primary management of perforated NEC in the very low birth weight infantJournal of Pediatric Surgery, 1994
- Necrotizing enterocolitis in very low birth weight infants: Biodemographic and clinical correlatesThe Journal of Pediatrics, 1991
- Necrotizing EnterocolitisNew England Journal of Medicine, 1984
- Peritoneal drainage under local anesthesia for perforations from necrotizing enterocolitisJournal of Pediatric Surgery, 1977