Detection of the KPC Gene in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii during a PCR-Based Nosocomial Surveillance Study in Puerto Rico
- 1 June 2011
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 55 (6), 2968-2970
- https://doi.org/10.1128/aac.01633-10
Abstract
A 6-month, PCR-based, island-wide hospital surveillance study of beta-lactam resistance in Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii was conducted in Puerto Rico. Of 10,507 isolates, 1,239 (12%) unique, multi-beta-lactam-resistant isolates from all geographical regions were identified. The KPC gene was detected in 61 E. coli, 333 K. pneumoniae, 99 P. aeruginosa, and 41 A. baumannii isolates, indicating the widespread dissemination of the KPC gene in clinically significant nosocomial isolates.Keywords
This publication has 13 references indexed in Scilit:
- Alarming β-lactamase-mediated resistance in multidrug-resistant EnterobacteriaceaeCurrent Opinion in Microbiology, 2010
- Outbreak of Carbapenem-Resistant Klebsiella pneumoniae in Puerto Rico Associated with a Novel Carbapenemase VariantInfection Control & Hospital Epidemiology, 2010
- Antimicrobial Susceptibility Patterns of KPC-Producing or CTX-M-Producing EnterobacteriaceaeMicrobial Drug Resistance, 2010
- Detection of KPC in Acinetobacter spp. in Puerto RicoAntimicrobial Agents and Chemotherapy, 2010
- The real threat of Klebsiella pneumoniae carbapenemase-producing bacteriaThe Lancet Infectious Diseases, 2009
- Surveillance of Carbapenem-Resistant Pseudomonas aeruginosa Isolates from Puerto Rican Medical Center Hospitals: Dissemination of KPC and IMP-18 β-LactamasesAntimicrobial Agents and Chemotherapy, 2009
- Genetic Structures at the Origin of Acquisition of the β-Lactamase bla KPC GeneAntimicrobial Agents and Chemotherapy, 2008
- Carbapenemases: the Versatile β-LactamasesClinical Microbiology Reviews, 2007
- First Identification of Pseudomonas aeruginosa Isolates Producing a KPC-Type Carbapenem-Hydrolyzing β-LactamaseAntimicrobial Agents and Chemotherapy, 2007
- A comparison of the antimicrobial resistance patterns of gram-negative bacilli isolated from community-private and university-affiliated hospitals from Puerto Rico.2003