Homozygous mouse embryos produced by microsurgery
- 1 August 1977
- journal article
- research article
- Published by Wiley in Journal of Experimental Zoology
- Vol. 201 (2), 295-302
- https://doi.org/10.1002/jez.1402010213
Abstract
Homozygous mouse blastocysts have been produced following microsurgical removal of one pronucleus from the fertilized egg, diploidization in cytochalasin B, and culture in vitro. This combination of techniques should greatly shorten the time required to obtain homozygous strains of mice.This publication has 6 references indexed in Scilit:
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- Efficiency of Transplanting Normal, Zona-Free, and Chimeric Embryos to One and Both Uterine Horns of Inbred and Hybrid Mice12Biology of Reproduction, 1973
- Tetraploid Mouse Embryos produced by Cytochalasin B during CleavageNature, 1973
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