Influence of polyunsaturated fatty acids on survival of skin allografts and tumor incidence in mice.
- 1 March 1976
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 73 (3), 928-931
- https://doi.org/10.1073/pnas.73.3.928
Abstract
S.c. or oral administration of the polyunsaturated fatty acid linoleic acid prolonged survival of skin allografts in mice. Mice fed on a diet deficient in polyunsaturated fatty acids showed a relative immunopotentiation, as indicated by accelerated skin allograft rejection and decreased incidence and rate of development of methylcholanthrene-induced tumors. Polyunsaturated fatty acids apparently take part in immunoregulatory mechanisms.This publication has 8 references indexed in Scilit:
- Specific Inhibitory Action of Polyunsaturated Fatty Acids on Lymphocyte Transformation Induced by PHA and PPDInternational Archives of Allergy and Immunology, 1975
- PROLONGATION OF SKIN ALLOGRAFTS IN RATS BY TREATMENT WITH LINOLEIC ACIDThe Lancet, 1974
- In-vitro inhibition by unsaturated fatty acids of the PPD- and PHA-induced lymphocyte responseKlinische Wochenschrift, 1974
- High levels of free fatty acids in lymphoid cells, with special reference to their cytotoxicityCellular and Molecular Life Sciences, 1973
- Long Term Effects on Immune Function of Early Nutritional DeprivationNature, 1973
- The effects of a series of prostaglandins on in vitro models of the allergic response and cellular immunityProstaglandins, 1972
- IMMUNE RESISTANCE AND MALNUTRITIONThe Lancet, 1972
- Absence of Enhancing Antibody in Cell Mediated Immunity to Tumour Heterografts in Protein Deficient RatsNature, 1971