Studies of the Rate of Transfer of Rb 86 , K 39 , Na 24 , Na 23 . Cl 36 , and Cl 35 Across the Pericardium of Dogs

Abstract

Studies of the simultaneous rates of transfer of various tracers and stable isotopes from the pericardium of normal dogs under pentobarbital anesthesia indicated that the rate of transfer of Rb⁸⁶ was greater than that of Na²⁴ and Cl³⁶, which were approximately equal. These observations show the pericardium to be a very active serous membrane concerned with electrolyte transfer phenomena as well as an excellent experimental model for the study of the kinetics of exchange of electrolytes across a normal living membrane.