Reduced Antibody Forming Capacity During the Incubation Period of Passage A Leukemia in C3H Mice.

Abstract

Summary Injection of Gross's passage A leukemia virus in newborn C₃H_f/Bi mice interferes with the development of their responsiveness to bacteriophage T₂. This deficiency was present in mice antigenically stimulated at 3 weeks and 9 weeks of age, and, notably, before obvious malignant cells are present.