Egress of CD19+CD5+ cells into peripheral blood following treatment with the Bruton tyrosine kinase inhibitor ibrutinib in mantle cell lymphoma patients
Top Cited Papers
Open Access
- 3 October 2013
- journal article
- clinical trial
- Published by American Society of Hematology in Blood
- Vol. 122 (14), 2412-2424
- https://doi.org/10.1182/blood-2013-02-482125
Abstract
Key Points MCL cells are mobilized into the peripheral blood of patients treated with the BTK inhibitor ibrutinib. Ibrutinib dose-dependently inhibits BCR- and chemokine-mediated adhesion and migration of MCL cells.Keywords
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