Phosphorylation of phosphodiesterase‐5 by cyclic nucleotide‐dependent protein kinase alters its catalytic and allosteric cGMP‐binding activities
Open Access
- 1 May 2000
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 267 (9), 2760-2767
- https://doi.org/10.1046/j.1432-1327.2000.01297.x
Abstract
In addition to its cGMP‐selective catalytic site, cGMP‐binding cGMP‐specific phosphodiesterase (PDE5) contains two allosteric cGMP‐binding sites and at least one phosphorylation site (Ser92) on each ...Keywords
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