Abstract
A modification of Frank's cancellation data-matching method for location of the QRS electric heart center in the human was applied to 40 patients, most of whom had advanced cardiac disease. The equivalent dipole locations for the QRS complex were found to cluster in a 5 cm. by 5 cm. square area forward and to the left in the transverse plane. Correlation of electric heart center location with orthodiagraphic estimate of the center of ventricular mass was poor in many of the cases.

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