SYNTHESIS OF AMIDES FROM ESTERS AND AMINES UNDER MICROWAVE IRRADIATION
- 1 January 2002
- journal article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 32 (22), 3525-3531
- https://doi.org/10.1081/scc-120014792
Abstract
Formamide, primary and secondary amines react with esters in the presence of potassium tert-butoxide under microwave irradiation. Substituted amides are formed in yields (generally more than 70%) much higher than under conventional heating.Keywords
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