Double‐blind comparison of primidone and phenobarbital in essential tremor
- 1 May 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 38 (5), 808
- https://doi.org/10.1212/wnl.38.5.808
Abstract
In a double-blind cross-over trial, primidone was superior to both placebo and phenobarbital in reducing essential tremor in 13 patients. Phenobarbital, at a dosage yielding serum barbiturate levels greater than those seen with primidone, was not better than placebo. Thus, primidone has an effect in essential tremor independent from that of its metabolite phenobarbital.This publication has 6 references indexed in Scilit:
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