GRANULOMA COCCIDIOIDES

Abstract
It is our purpose to present evidence supporting that brought forth previously, first by Guy and Jacob1and later by ourselves,2indicating that antimony and potassium tartrate, given intravenously, combined with roentgen therapy, applied locally, is of value in the treatment of granuloma coccidioides. In 1927 Guy and Jacob reported the first apparent cure of coccidioidal granuloma by means of these measures. Their patient had shown little or no improvement under various other forms of treatment, including iodides and the roentgen rays. Four months' treatment on alternate days, using a 1 per cent solution of antimony and potassium tartrate in doses up to 7 cc., apparently resulted in complete healing. Roentgen therapy was used during these four months in one-half unit doses at ten day intervals. A month after treatment was discontinued the disease recurred, but subsided fairly promptly "with a few tartar emetic and roentgen treatments." These