Presence of messenger specifying sequences in the DNA of chromatin subunits.

Abstract
Messenger-specifying sequences in subunits of human lymphocyte chromatin were detected by hybridization of DNA complementary to cytoplasmic polyadenylated RNA with DNA isolated from the subunits. Comparison of the kinetics and extents of hybridization of complementary DNA with chromatin subunit DNA and with nuclear DNA showed that most of the repetitive sequences and single copy sequences in mRNA are present in chromatin subunits. Inclusion of a DNA sequence into the subunit apparently does not prevent its transcription in vivo.