Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivo
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Open Access
- 1 March 2005
- journal article
- research article
- Published by Elsevier in Molecular Therapy
- Vol. 11 (3), 418-425
- https://doi.org/10.1016/j.ymthe.2004.11.006
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Polyacetal−Doxorubicin Conjugates Designed for pH-Dependent DegradationBioconjugate Chemistry, 2003
- Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG–lipidsJournal of Controlled Release, 2003
- Low-pH-Sensitive PEG-Stabilized Plasmid−Lipid Nanoparticles: Preparation and CharacterizationBioconjugate Chemistry, 2003
- Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID miceHepatology, 2002
- Nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimineBiochimica et Biophysica Acta (BBA) - General Subjects, 2002
- Importance of Lateral and Steric Stabilization of Polyelectrolyte Gene Delivery Vectors for Extended Systemic CirculationMolecular Therapy, 2002
- DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expressionAAPS PharmSci, 2001
- Coupling of cell-binding ligands to polyethylenimine for targeted gene deliveryGene Therapy, 1997
- Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene DeliveryHuman Gene Therapy, 1996
- Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligandBioconjugate Chemistry, 1992