Straightforward route to 2- and 3-formyl hex-1- and -2-enopyranosides and their highly stereoselective hetero Diels–Alder reaction with ethyl vinyl ether

Abstract

A straightforward route from D-glucose to conjugated enal and diene pyranoses through a dithiane-based methodology is disclosed; hetero Diels–Alder reaction of the enals with ethyl vinyl ether occurs with high stereoselectivity.