Abstract
The Changing Pattern of SynthesisThe conversion of an oocyte to an ovum is more than a process of growth. Recent attempts to identify some of the macromolecular working parts of an egg, and to specify some of the locations provided for them during oogenesis, represent no discontinuity with the embryologic past, since it has been understood for a long time that the purposeful operations of early development are in large measure the working out of a program built into the cytoplasm of the egg.55 It is a more recent idea that the program can at least in part be . . .