Protection of cysteine and histidine by the diphenyl-4-pyridylmethyl group during peptide synthesis

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Abstract
The diphenyl-4-pyridylmethyl group provides acid-stable protection of the thiol group of cysteine and the imidazole-nitrogen of histidine; it is removed by reductive methods (including electrolytic reduction) and from thiols by mercury(II) acetate and by iodine.