THE MITOTIC SPINDLE APPARATUS OFNEUROSPORA CRASSA

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Abstract
Electron microscopic studies of the sl-327 mutant of Neurospora crassa reveal that somatic nuclear division in hyphlet somatic cells involves a definite spindle apparatus consisting of spindle microtubules terminating at specific loci on the external surface of the nuclear envelope. These loci, termed spindle plaques, have been observed in a variety of other fungal species and seem to play a role in the initiation of spindle microtubule growth during mitosis. The development of the various spindle components and their possible functions in nuclear division in this strain of Neurospora are discussed.