CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping
Open Access
- 14 December 2004
- journal article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 21 (8), 1703-1704
- https://doi.org/10.1093/bioinformatics/bti222
Abstract
Summary: Carh ta Gene: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. Carh ta Gene: performs multipoint maximum likelihood estimations with accelerated expectation–maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. Carh ta Gene: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.Keywords
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