Intracerebral hemorrhage outcome: Apolipoprotein E genotype, hematoma, and edema volumes
- 1 December 1999
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 53 (9), 2176
- https://doi.org/10.1212/wnl.53.9.2176
Abstract
Article abstract We investigated whether early hematoma or edema volumes could explain the adverse association between APOE ε4 and survival in intracerebral hemorrhage. Among 102 patients, ε4 carriers had a higher mortality rate than non–ε4 carriers (38 versus 24%, p = 0.05). Nonsurvivors had larger hematoma (75.5 cm3 versus 27.1 cm3, p < 0.001) and edema volumes (37.5 cm3 versus 17.1 cm3, p < 0.01), but these were not associated with ε4 after adjusting for race, age, and type of hemorrhage.Keywords
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