Decrease of Cardiac Mass Following Excess Dietary Potassium Chloride in the Rat

Abstract

Female Wistar rats were submitted to a 2.5% aqueous soln. of KCl as the sole source of fluid for 105 days, control animals receiving tap water. The cardiac mass of the KCl rats was lower, and the renal mass higher, than that of control animals. The cardio-renal changes, and histological and histochemical properties of the adrenals returned to normal in animals given tap water for 30 days following KCl flooding.