Intra-uterine Osteogenesis Imperfecta. Review of the literature and a report of the radiological and necropsy findings in two cases

Abstract

The condition of osteogenesis imperfecta congenita is briefly discussed and reviewed, there being no difference in the histological appearances of the various syndromes described. Two cases are described, one diagnosed in utero and the 2nd diagnosed after delivery. Necropsy findings in these cases are given and attention is drawn to associated abnormalities in the heart and the gut.