AGGRAVATION OF CHOLESTEROL ATHEROSCLEROSIS IN RABBITS BY FREE UNSATURATED FATTY ACIDS

Abstract
An unsaturated fatty acid preparation containing 90 to 95% linoleic acid was tested on cholesterol induced hyper-cholesterolemia and atherosclerosis in the rabbit. The rabbits, treated with cholesterol dissolved in the unsaturated fatty acid, revealed a significantly higher hypercholesterolemia and more marked atherosclerosis than the rabbits that were treated with cholesterol dissolved in the same amount of olive oil.