AUTORADIOGRAPHIC STUDIES OF THE DISTRIBUTION OF 1-AMINOCYCLOPENTANE CARBOXYLIC ACID IN NORMAL AND CANCEROUS MICE

Abstract

Normal and cancerous mice were injected with 1-aminocyclopentane C¹⁴-carboxylic acid and the distribution of the drug in the animals was studied by autoradiography. In normal mice, the amino acid is concentrated selectively by the pancreas and the bone marrow. In cancerous mice (Ehrlich ascites tumor and sarcoma-180), the tumor cells also intensively accumulate the amino acid.