Hypobaric Hypoxia-Induced Intrauterine Growth Retardation
- 1 January 1984
- journal article
- research article
- Published by S. Karger AG in Neonatology
- Vol. 46 (1), 10-14
- https://doi.org/10.1159/000242026
Abstract
2-week-pregnant New Zealand White rabbits were placed into a hypobaric chamber and maintained at 3,657 m (12,000 ft). Upon delivery (31 ± 1 days) or at cesarean section (on day 30), all newborns were sacrificed and organ weights were compared to those of control pups maintained at 128 m (420 ft). Significant findings in the hypobaric animals included a diminished birth weight, placental weight, and liver weight per body weight. Placental weight per body weight was similar in both groups. The brain weight per body weight, brain to liver ratio, and right ventricle to left ventricle plus intraventricular septal weight ratio were significantly increased in the hypobaric pups.This publication has 4 references indexed in Scilit:
- Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural featuresAmerican Journal of Physiology-Heart and Circulatory Physiology, 1979
- Placental diffusing capacity and fetal development in exercising or hypoxic guinea pigsJournal of Applied Physiology, 1979
- Fetal Growth Retardation and Increased Infant Mortaliy at High AltitideArchives of environmental health, 1977
- Chronic Fetal Distress and Placental Insufficiency (Part 1 of 3)Neonatology, 1963