BASAL SQUAMOUS CELL EPITHELIOMA ASSOCIATED WITH LEUKEMIA

Abstract

THE FIRST authentic case of the simultaneous occurrence of malignant disease and leukemia was described by Whipham in 1878. A total of 21 cases of combined leukemia and malignant growths had been reported up to 1944, according to Morrison, Feldman and Samwick.¹All the malignant growths involved internal organs except those in the cases of Fuhs,²Scheuffler³and Schreiner and Wehr,⁴who described epitheliomas of the skin. While Schreiner and Wehr described a case of epithelioma of the ear, associated with chronic lymphatic leukemia, originating on a normal skin, the epitheliomas described by Fuhs and Scheuffler developed on a leukemid. Besides these reports, Schreiner and Wehr had, among 11,212 cases of malignant disease, an additional 4 cases. Since the association of leukemia with malignant growth, particularly the combination with cancer of the skin, is rare, we deemed it to be of sufficient interest to report the