THE EFFECT OF VARIOUS HORMONES UPON THE HEPATIC SYNTHESIS OF CHOLESTEROL IN RATS*
- 1 August 1952
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 51 (2), 142-147
- https://doi.org/10.1210/endo-51-2-142
Abstract
The biliary concn. of cholesterol previously was shown to be an indicator of hepatic synthesis of cholesterol in rats. This method was used to study the influence of ACTH, adrenocortical steroids, and the sex hormones. Hepatic synthesis of cholesterol in rats is apparently depressed by estrogenic hormone and augmented by ACTH. None of the prepns. had any effect upon bile volume output, biliary excretion of cholate, or upon plasma cholesterol levels.Keywords
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