ECCRINE FUNCTION IN PSORIASIS INVERSUS

Abstract

Patients with psoriatic lesions of the axilla and the interanal cleft were examined by the quinizarin test for sweating (thermal and intradermal methacholine stimulation) to determine whether these areas were anhidrotic and to explain the source of moisture causing maceration and absence of scaling in psoriasis inversus. Histo-pathological changes in the biopsy specimens were consistent with psoriasis inversus and these lesions were anhidrotic. Maceration was attributed to the spread of sweat from adjacent uninvolved skin, spongiosis and vesiculation, serum exudation, and insensible perspiration.