Potentiating Effect of Nocardia asteroides on Sensitization to Picryl Chloride and on Production of Isoallergic Encephalomyelitis

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Abstract
Killed N. asteroides can replace mycobacteria as an adjuvant in the production of 1) skin sensitization to picryl chloride, and 2) isoallergic meningo-encephalitis. Killed N. asteroides in water-in-oil emulsion induces a delayed type of sensitization to an extract from this fungus. Killed N. asteroides in water-in-oil emulsion sensitizes to tuberculin. The degree of sensitization is slight when compared with that produced by killed Mycobac-terium tuberculosis in oil.